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The US Department of Health and Services coined the term prediabetes on 27 March 2002 to make people realize the seriousness of the upcoming disease in their life. It is the stage before the disease is actually diagnosed. Borderline diabetes, chemical diabetes, touch of diabetes is few names, which are given to the stage known as prediabetes by the doctors. This is the actual stage when one should start modifying their life and take precautions to prevent it. Hyponatremia secondary to the syndrome of inappropriate secretion of antidiuretic hormone SIADH is an uncommon complication of treatment with the new class of antidepressant agents, the selective serotonin reuptake inhibitors SSRIs. Most of the reported cases were associated with fluoxetine; only 2 have previously been described in association with citalopram. We describe an elderly woman who presented with severe symptomatic hyponatremia caused by the SIADH during therapy with citalopram. Because the use of SSRIs is becoming more popular among elderly depressed patients, the present case and the other 2 reported previously emphasize the need for greater awareness of the development of this serious and potentially fatal complication also in association with citalopram therapy and suggest that serum sodium levels should be monitored closely in elderly patients during treatment with citalopram.

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Posted by at June 6, 2015
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